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Therapies for Systolic Hypertension

Published: February 11, 2009

Dear Dr. SerVaas,

I’m diabetic and have systolic hypertension. My systolic pressure runs from 115 to 120 in the morning and 120 to 170 in the evening. I’ve included a list of the medicines I have tried. Is there anything in the pipeline for my condition?


Post cardiology consultant Dr. Douglas Zipes replies:

“You have certainly been through a bunch of medications, but there are others you have not tried. For example, carvedilol is a unique type of beta blocker that has alpha and beta blocking actions. Pure alpha blockers like Cardura (doxazosin) might work. Other diuretics might be effective, as can combinations of drugs that have different actions. Finally, you don’t mention lifestyle modifications, and they should be considered. These can include a low-salt diet, potassium supple¬ments, moderate alcohol consumption, weight loss, exercise, and relaxation techniques. Check with your cardiologist or hypertensive expert.”

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