To A.S., Rice Lake, Wisconsin:
Long-term use of drugs called proton pump inhibitors (such as Aciphex) for acid reflux is seen by most as a safe choice that is made on a case-by-case basis. There is some evidence that the decrease in acid in the stomach increases a person’s risk of pneumonia. The lower level of stomach acid may also decrease the body’s ability to absorb calcium and vitamin B12, nutrients that are important for bone health, energy, and metabolism. Ask your doctor whether monitoring these key compounds might be indicated.