Recent medical findings show that lower doses of prescription colchicine treat gout just as well as the higher amounts used in past years—and with fewer side effects. Instead of 10 tablets per day, doctors now recommend taking two tablets at the first signs of an attack, followed by one tablet an hour later, if needed. Colchicine interacts with a number of medications, notably the antibiotic clarithromycin (Biaxin). Ask your pharmacist or doctor about possible drug interactions before starting colchicine treatment.
Gout: New Therapy Guidelines