A new study shows that Botox therapy may reduce pressure and help relieve chronic lower abdominal pain in women with pelvic floor spasms. Compared with placebo shots, injecting Botox into pelvic floor muscles was linked to a significant reduction in pelvic pain at 26-week follow-up. The promising findings, reported by Dr. Jason Abbott from the Royal Hospital for Women in Randwick, Australia, are published in the October 2006 issue of Obstetrics and Gynecology. As we go to press, researchers at the University of Washington are recruiting patients to explore the use of Botox in men with chronic pelvic pain syndrome and women with interstitial cystitis. Log on to clinicaltrials.gov and enter "botox, pelvic pain" for more information about the studies.